venerdì 12 luglio 2019

OPEN CALL for 1 Research Fellow position (12 months)

PERIPHERAL IMMUNITY IN AGING AND PARKINSON’S DISEASE

OPEN CALL for 1 Research Fellow position (12 months)

The Center for Research in Medical Pharmacology, University of Insubria (Varese, Italy), and the Movement Disorders Centre, Neurology Unit, Department of Translational Medicine, University of Piemonte Orientale (Novara, Italy), have an open Research Fellow position to work on the role of peripheral immunity in aging and Parkinson's disease, with particular regard to T cells as biomarkers of immunoaging and their relationship with frailty and PD progression.
 
The ideal candidate for this
Research Fellow position is expected to hold an MD or BSc degree or similar, and to have adequate experience in biomedical research. In particular, s/he is expected to learn and apply:
- flow cytometry techniques for the characterization of main innate and adaptive immune cell subsets in whole blood;
- cell separation and culture protocols, with particular regard to human T lymphocyte purification and culture from buffy coats and whole blood;
- ex vivo/in vitro functional models of immune response.
Knowledge of scientific english and documented ability to write scientific reports and manuscripts will be a preferential requirement.

The position will be last for 12 months. Salary will be 1.200,00 €/month (net amount). The position might be extended for additional 12 months upon positive assessment of results and availability of funds.



For detailed information about rules that will apply to the position please see here.

An official call detailing deadlines and procedures will be soon available. Potential applicants are meanwhile invited to submit a preapplication/motivation letter, together with a curriculum vitae including a full list of publications and eventual names for references, at their earliest convenience, to farmacologia.medica@uninsubria.it. E-mail submissions must include the subject “Research Fellow position”.

References
Storelli E, Cassina N, Rasini E, Marino F, Cosentino M. Do Th17 Lymphocytes and IL-17 Contribute to Parkinson's Disease? A Systematic Review of Available Evidence. Front. Neurol., 24 January 2019 | https://doi.org/10.3389/fneur.2019.00013
Kustrimovic N, Comi C, Magistrelli L, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Minafra B, Riboldazzi G, Sturchio A, Mauri M, Bono G, Marino F, Cosentino M. Parkinson's disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients. J Neuroinflammation. 2018 Jul 12;15(1):205. doi: 10.1186/s12974-018-1248-8.
Cosentino M, Kustrimovic N, Marino F. β2-Adrenergic Agonists for Parkinson’s Disease: Repurposing Drugs at the Crossroad of the Brain and the Immune System. BrainImmune - Trends in Neuroendocrine Immunology (online), 2 december 2017.
Kustrimovic N, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Comi C, Mauri M, Minafra B, Riboldazzi G, Sanchez-Guajardo V, Marino F, Cosentino M. Dopaminergic Receptors on CD4+ T Naive andMemory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson'sDisease. Sci Rep. 2016 Sep 22;6:33738.
Marino F, Cosentino M. Multiple sclerosis:Repurposing dopaminergic drugs for MS--the evidence mounts. Nat Rev Neurol. 2016 Apr;12(4):191-2.

domenica 7 luglio 2019

OPEN CALL for 1 PhD Fellow position (36 months)

PERIPHERAL IMMUNITY IN PARKINSON’S DISEASE

OPEN CALL for 1 PhD Fellow position (36 months)

The Center for Research in Medical Pharmacology, University of Insubria (Varese, Italy) has an open PhD fellowship position to work on the role of peripheral immunity in Parkinson's disease with particular regard its relationship with neuroinflammation and neurodegeneration.

The ideal candidate for this PhD fellowship position (dottorato di ricerca) is expected to hold an MD or BSc degree or similar. During the PhD fellowship, s/he will learn and apply:
- flow cytometry techniques for the characterization of main innate and adaptive immune cell subsets in whole blood;
- cell separation and culture protocols, with regard to human granulocytes, monocytes and T lymphocytes purification and culture from buffy coats and whole blood;
- ex vivo/in vitro functional models of immune response;
- how to write scientific reports and manuscripts.
Knowledge of scientific english is an absolute requirement.

The position is open for 36 months. Salary will be 65.956,16 €/3 years (including taxes/social security and 6 months increase for travelling abroad).


The profile of the PhD program in Clinical and Experimental Medicine and Medical Humanities is available at:

The official call detailing deadlines and procedures is available at:
- https://www.uninsubria.it/opportunita/ammissione-ai-dottorati-di-ricerca-xxxv-ciclo-aa-20192020 (italian)
- https://www.uninsubria.eu/opportunity/call-phd-xxxv (english)
Please refer to PhD program in Clinical and Experimental Medicine and Medical Humanities.
Deadline for application: 31 July 2019.

For more information please contact: farmacologia.medica@uninsubria.it.
E-mail submissions must include the subject “PhD position”.


References
Storelli E, Cassina N, Rasini E, Marino F, Cosentino M. Do Th17 Lymphocytes and IL-17 Contribute to Parkinson's Disease? A Systematic Review of Available Evidence. Front. Neurol., 24 January 2019 | https://doi.org/10.3389/fneur.2019.00013
Kustrimovic N, Comi C, Magistrelli L, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Minafra B, Riboldazzi G, Sturchio A, Mauri M, Bono G, Marino F, Cosentino M. Parkinson's disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients. J Neuroinflammation. 2018 Jul 12;15(1):205. doi: 10.1186/s12974-018-1248-8.
Cosentino M, Kustrimovic N, Marino F. β2-Adrenergic Agonists for Parkinson’s Disease: Repurposing Drugs at the Crossroad of the Brain and the Immune System. BrainImmune - Trends in Neuroendocrine Immunology (online), 2 december 2017.
Kustrimovic N, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Comi C, Mauri M, Minafra B, Riboldazzi G, Sanchez-Guajardo V, Marino F, Cosentino M. Dopaminergic Receptors on CD4+ T Naive andMemory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson'sDisease. Sci Rep. 2016 Sep 22;6:33738.
Marino F, Cosentino M. Multiple sclerosis:Repurposing dopaminergic drugs for MS--the evidence mounts. Nat Rev Neurol. 2016 Apr;12(4):191-2.

martedì 12 giugno 2018

OPEN CALL for 1 PhD Fellow position (36 months)

PERIPHERAL IMMUNITY IN PARKINSON’S DISEASE

OPEN CALL for 1 PhD Fellow position (36 months)

The Center for Research in Medical Pharmacology, University of Insubria (Varese, Italy) has an open PhD fellowship position to work on the role of peripheral immunity in Parkinson's disease with particular regard its relationship with neuroinflammation and neurodegeneration.

The ideal candidate for this PhD fellowship position (dottorato di ricerca) is expected to hold an MD or BSc degree or similar. During the PhD fellowship, s/he will learn and apply:
- flow cytometry techniques for the characterization of main innate and adaptive immune cell subsets in whole blood;
- cell separation and culture protocols, with regard to human granulocytes, monocytes and T lymphocytes purification and culture from buffy coats and whole blood;
- ex vivo/in vitro functional models of immune response;
- how to write scientific reports and manuscripts.
Knowledge of scientific english is an absolute requirement.

The position is open for 36 months. Salary will be 65.956,16 €/3 years (including taxes/social security and 6 months increase for travelling abroad).

The official call detailing deadlines and procedures is available at:
- https://www.uninsubria.it/bandodottorati (italian)
- https://www.uninsubria.eu/programs/phd-doctoral-research (english)
Please refer to PhD program in Clinical and Experimental Medicine and Medical Humanities.
Deadline for application: 31 July 2018.

For more information please contact: farmacologia.medica@uninsubria.it.
E-mail submissions must include the subject “PhD position”.


References
Cosentino M, Kustrimovic N, Marino F. β2-Adrenergic Agonists for Parkinson’s Disease: Repurposing Drugs at the Crossroad of the Brain and the Immune System. BrainImmune - Trends in Neuroendocrine Immunology (online), 2 december 2017.
Kustrimovic N, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Comi C, Mauri M, Minafra B, Riboldazzi G, Sanchez-Guajardo V, Marino F, Cosentino M. Dopaminergic Receptors on CD4+ T Naive andMemory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson'sDisease. Sci Rep. 2016 Sep 22;6:33738.
Marino F, Cosentino M. Multiple sclerosis:Repurposing dopaminergic drugs for MS--the evidence mounts. Nat Rev Neurol. 2016 Apr;12(4):191-2.

lunedì 22 gennaio 2018

OPEN CALL for 1 Post Doc Research Fellow position (12+12 months)

PERIPHERAL IMMUNITY IN AGING AND PARKINSON’S DISEASE

OPEN CALL for 1 Post Doc Research Fellow position (12+12 months)

The Center for Research in Medical Pharmacology, University of Insubria (Varese, Italy) works on the role of peripheral immunity in aging and Parkinson's disease with particular regard to T cells as biomarkers of immunoaging and their relationship with frailty and PD progression.

The ideal candidate for this Post Doc Research Fellow position (assegno di ricerca) is expected to hold an MD or BSc degree or similar, and to have extensive experience in biomedical research, documented by an appropriate record of publications. In particular, s/he is expected to learn and apply:
- flow cytometry techniques for the characterization of main innate and adaptive immune cell subsets in whole blood;
- cell separation and culture protocols, with particular regard to human T lymphocyte purification and culture from buffy coats and whole blood;
- ex vivo/in vitro functional models of immune response.
Knowledge of scientific english and documented ability to write scientific reports and manuscripts will be a preferential requirement.

The position is open for 1+1 years. Salary will be 25.000,00 €/year (including taxes/social security).

An official call detailing deadlines and procedures will be soon available. Potential applicants are meanwhile invited to submit a preapplication/motivation letter, together with a curriculum vitae including a full list of publications and eventual names for references, at their earliest convenience and possibly not later than February 28th 2018, to farmacologia.medica@uninsubria.it. E-mail submissions must include the subject “Post Doc position”.

References
Cosentino M, Kustrimovic N, Marino F. β2-Adrenergic Agonists for Parkinson’s Disease: Repurposing Drugs at the Crossroad of the Brain and the Immune System. BrainImmune - Trends in Neuroendocrine Immunology (online), 2 december 2017.
Kustrimovic N, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Comi C, Mauri M, Minafra B, Riboldazzi G, Sanchez-Guajardo V, Marino F, Cosentino M. Dopaminergic Receptors on CD4+ T Naive andMemory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson'sDisease. Sci Rep. 2016 Sep 22;6:33738.
Marino F, Cosentino M. Multiple sclerosis:Repurposing dopaminergic drugs for MS--the evidence mounts. Nat Rev Neurol. 2016 Apr;12(4):191-2.

 

mercoledì 18 ottobre 2017

La ricerca scientifica sulla Malattia di Parkinson a Varese - Risultati e prospettive

https://drive.google.com/file/d/0B6z7burLdR0QLWlVemREZmx0T3c/view?usp=sharing

Fare click sull'immagine per visualizzare e scaricare il volume in .pdf (3 Mb)

NB: Google Drive potrebbe non visualizzare il file in determinati browser. E' comunque possibile scaricare il volume sul proprio terminale utilizzando il comando "scarica" solitamente disponibile sulla parte superiore destra dello schermo.